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Clinical Epidemiology and Ageing

HIV infection and COVID-19: risk factors for severe disease.

Etienne N, Karmochkine M, Slama L, Pavie J, Batisse D, Usubillaga R, Letembet V-A, Brazille P, Canouï E, Slama D, Joumaa H, Canoui-Poitrine F, Segaux L, Weiss L, Viard J-P, Salmon D AIDS. 2020;34(12):1771-1774.

: We performed an observational prospective monocentric study in patients living with HIV (PLWH) diagnosed with COVID-19. Fifty-four PLWH developed COVID-19 with 14 severe (25.9%) and five critical cases (9.3%), respectively. By multivariate analysis, age, male sex, ethnic origin from sub-Saharan Africa and metabolic disorder were associated with severe or critical forms of COVID-19. Prior CD4 T cell counts did not differ between groups. No protective effect of a particular antiretroviral class was observed.

MeSH terms: Adult; Africa South of the Sahara; Anti-Retroviral Agents; CD4 Lymphocyte Count; Coronavirus Infections; Female; France; HIV Infections; Humans; Logistic Models; Male; Metabolic Diseases; Middle Aged; Multivariate Analysis; Pandemics; Pneumonia, Viral; Prospective Studies; Risk Assessment; Risk Factors
DOI: 10.1097/QAD.0000000000002651