cepia

Clinical Epidemiology and Ageing

I-O Optimise: a novel multinational real-world research platform in thoracic malignancies.

Ekman S, Griesinger F, Baas P, Chao D, Chouaid C, O'Donnell JC, Penrod JR, Daumont M, Lacoin L, McKenney A, Khovratovich M, Munro REj, Durand-Zaleski I, Johnsen SPaaske Future Oncol. 2019;15(14):1551-1563.

To describe I-O Optimise, a multinational program providing real-world insights into lung cancer management. Real-world data source selection for I-O Optimise followed a structured approach focused on population coverage, key variable capture, continuous/consistent data availability, record duration and data latency, and database expertise.  As of 31 October 2018, seven real-world data sources were included in I-O Optimise, providing data on characteristics, treatment patterns and clinical outcomes from more than 45,000 patients/year with non-small-cell lung cancer, small-cell lung cancer and mesothelioma across Denmark, Norway, Portugal, Spain, Sweden and the UK. The ongoing I-O Optimise initiative has the potential to provide a broad, robust and dynamic research platform to continually address numerous research objectives in the lung cancer arena.

MeSH terms: Databases, Factual; Disease Management; Europe; Global Health; Humans; Lung Neoplasms; Medical Informatics; Patient Care; Patient Outcome Assessment; Practice Patterns, Physicians'; Public Health Surveillance; Research; Thoracic Neoplasms
DOI: 10.2217/fon-2019-0025