To describe I-O Optimise, a multinational program providing real-world insights into lung cancer management. Real-world data source selection for I-O Optimise followed a structured approach focused on population coverage, key variable capture, continuous/consistent data availability, record duration and data latency, and database expertise. As of 31 October 2018, seven real-world data sources were included in I-O Optimise, providing data on characteristics, treatment patterns and clinical outcomes from more than 45,000 patients/year with non-small-cell lung cancer, small-cell lung cancer and mesothelioma across Denmark, Norway, Portugal, Spain, Sweden and the UK. The ongoing I-O Optimise initiative has the potential to provide a broad, robust and dynamic research platform to continually address numerous research objectives in the lung cancer arena.
I-O Optimise: a novel multinational real-world research platform in thoracic malignancies.
Future Oncol. 2019;15(14):1551-1563.
MeSH terms: Databases, Factual; Disease Management; Europe; Global Health; Humans; Lung Neoplasms; Medical Informatics; Patient Care; Patient Outcome Assessment; Practice Patterns, Physicians'; Public Health Surveillance; Research; Thoracic Neoplasms
DOI: 10.2217/fon-2019-0025